- Notice: Undefined index: title_shortcut in Drupal\esante_sommaire\EsanteSommaireUtils::decoupe_node() (line 84 of modules/custom/sommaire/src/EsanteSommaireUtils.php).
Drupal\esante_sommaire\EsanteSommaireUtils::decoupe_node('$$Quelles sont les précautions particulières à prendre ?$$Il est préférable d'être à jeun avant le prélèvement de sang. $$En quoi consiste cette analyse ?$$<strong>L'immunofixation</strong> consiste à déposer du plasma (ou de l'urine qui aura au préalable été concentrée) sur un gel. Après application d'un courant électrique qui permet la séparation des protéines en fonction de leur taille, des anticorps spécifiques de chaque type d'immunoglobuline sont déposés sur le gel. Il apparaît ainsi des bandes plus ou moins étroites sur le gel, au niveau où se situent les différentes immunoglobulines.<strong>L'immunoélectrophorèse</strong> est une autre technique permettant la mise en évidence et le typage des immunoglobulines monoclonales. Elle est aujourd'hui moins utilisée car moins sensible que l'immunofixation.$$A quoi sert ce dosage ?$$<strong>L'immunofixation</strong> est la technique la plus fine pour détecter une immunoglobuline monoclonale. La présence de l'immunoglobuline peut révéler une hémopathie ou bien être bénigne (comme cela est assez fréquemment observé chez les personnes âgées). Une immunoglobuline monoclonale est souvent dépistée cours d'une électrophorèse des protéines urinaires ou d'une ##66999/électrophorèse des protéines plasmatique/##. Parfois, l'immunofixation la révèle lorsqu'elle est passée inaperçue à l'électrophorèse, en particulier lorsqu'elle est présente en petite quantité (moins d'1 gramme/litre). L'immunofixation permet aussi de la typer (en IgG, IgM,...) ce qui aide au diagnostic de la maladie en cause. Enfin, elle participe à la surveillance des patients chez qui a été mise en évidence une telle "immunoglobuline". $$Quelles sont les valeurs normales ?$$La présence d'une bande étroite sur le gel permet de caractériser une immunoglobuline monoclonale.$$Comment est interprété le résultat ?$$<ul><li> Le dépistage et l'identification d'une immunoglobuline monoclonale dans le sang par l'immunofixation (ou l'immunoélectrophorèse) nécessitent de poursuivre les investigations à la recherche d'une éventuelle hémopathie maligne.</li> </ul> <ul><li> Dans les urines peuvent être retrouvée(s) une immunoglobuline monoclonale entière et/ou une ##14755/protéine de Bence-Jones/##, fragment d'immunoglobuline monoclonale. Leur identification permet, de la même façon, d'évoquer un diagnostic d'hémopathie maligne qui devra également être confirmé par d'autres examens.</li> </ul><a href="#top">haut de page</a>', 2, '14455') (Line: 51)
esante_sommaire_node_view(Array, Object, Object, 'full')
call_user_func_array('esante_sommaire_node_view', Array) (Line: 403)
Drupal\Core\Extension\ModuleHandler->invokeAll('node_view', Array) (Line: 299)
Drupal\Core\Entity\EntityViewBuilder->buildMultiple(Array) (Line: 250)
Drupal\Core\Entity\EntityViewBuilder->build(Array)
call_user_func_array(Array, Array) (Line: 100)
Drupal\Core\Render\Renderer->doTrustedCallback(Array, Array, 'Render #pre_render callbacks must be methods of a class that implements \Drupal\Core\Security\TrustedCallbackInterface or be an anonymous function. The callback was %s. Support for this callback implementation is deprecated in 8.8.0 and will be removed in Drupal 9.0.0. See https://www.drupal.org/node/2966725', 'silenced_deprecation', 'Drupal\Core\Render\Element\RenderCallbackInterface') (Line: 781)
Drupal\Core\Render\Renderer->doCallback('#pre_render', Array, Array) (Line: 372)
Drupal\Core\Render\Renderer->doRender(Array, ) (Line: 200)
Drupal\Core\Render\Renderer->render(Array, ) (Line: 226)
Drupal\Core\Render\MainContent\HtmlRenderer->Drupal\Core\Render\MainContent\{closure}() (Line: 573)
Drupal\Core\Render\Renderer->executeInRenderContext(Object, Object) (Line: 227)
Drupal\Core\Render\MainContent\HtmlRenderer->prepare(Array, Object, Object) (Line: 117)
Drupal\Core\Render\MainContent\HtmlRenderer->renderResponse(Array, Object, Object) (Line: 90)
Drupal\Core\EventSubscriber\MainContentViewSubscriber->onViewRenderArray(Object, 'kernel.view', Object)
call_user_func(Array, Object, 'kernel.view', Object) (Line: 111)
Drupal\Component\EventDispatcher\ContainerAwareEventDispatcher->dispatch('kernel.view', Object) (Line: 156)
Symfony\Component\HttpKernel\HttpKernel->handleRaw(Object, 1) (Line: 68)
Symfony\Component\HttpKernel\HttpKernel->handle(Object, 1, 1) (Line: 57)
Drupal\Core\StackMiddleware\Session->handle(Object, 1, 1) (Line: 47)
Drupal\Core\StackMiddleware\KernelPreHandle->handle(Object, 1, 1) (Line: 47)
Drupal\Core\StackMiddleware\ReverseProxyMiddleware->handle(Object, 1, 1) (Line: 52)
Drupal\Core\StackMiddleware\NegotiationMiddleware->handle(Object, 1, 1) (Line: 23)
Stack\StackedHttpKernel->handle(Object, 1, 1) (Line: 694)
Drupal\Core\DrupalKernel->handle(Object) (Line: 19)
- Notice: Undefined offset: 0 in esante_entity_view() (line 89 of modules/custom/esante/esante.module).
esante_entity_view(Array, Object, Object, 'full')
call_user_func_array('esante_entity_view', Array) (Line: 403)
Drupal\Core\Extension\ModuleHandler->invokeAll('entity_view', Array) (Line: 300)
Drupal\Core\Entity\EntityViewBuilder->buildMultiple(Array) (Line: 250)
Drupal\Core\Entity\EntityViewBuilder->build(Array)
call_user_func_array(Array, Array) (Line: 100)
Drupal\Core\Render\Renderer->doTrustedCallback(Array, Array, 'Render #pre_render callbacks must be methods of a class that implements \Drupal\Core\Security\TrustedCallbackInterface or be an anonymous function. The callback was %s. Support for this callback implementation is deprecated in 8.8.0 and will be removed in Drupal 9.0.0. See https://www.drupal.org/node/2966725', 'silenced_deprecation', 'Drupal\Core\Render\Element\RenderCallbackInterface') (Line: 781)
Drupal\Core\Render\Renderer->doCallback('#pre_render', Array, Array) (Line: 372)
Drupal\Core\Render\Renderer->doRender(Array, ) (Line: 200)
Drupal\Core\Render\Renderer->render(Array, ) (Line: 226)
Drupal\Core\Render\MainContent\HtmlRenderer->Drupal\Core\Render\MainContent\{closure}() (Line: 573)
Drupal\Core\Render\Renderer->executeInRenderContext(Object, Object) (Line: 227)
Drupal\Core\Render\MainContent\HtmlRenderer->prepare(Array, Object, Object) (Line: 117)
Drupal\Core\Render\MainContent\HtmlRenderer->renderResponse(Array, Object, Object) (Line: 90)
Drupal\Core\EventSubscriber\MainContentViewSubscriber->onViewRenderArray(Object, 'kernel.view', Object)
call_user_func(Array, Object, 'kernel.view', Object) (Line: 111)
Drupal\Component\EventDispatcher\ContainerAwareEventDispatcher->dispatch('kernel.view', Object) (Line: 156)
Symfony\Component\HttpKernel\HttpKernel->handleRaw(Object, 1) (Line: 68)
Symfony\Component\HttpKernel\HttpKernel->handle(Object, 1, 1) (Line: 57)
Drupal\Core\StackMiddleware\Session->handle(Object, 1, 1) (Line: 47)
Drupal\Core\StackMiddleware\KernelPreHandle->handle(Object, 1, 1) (Line: 47)
Drupal\Core\StackMiddleware\ReverseProxyMiddleware->handle(Object, 1, 1) (Line: 52)
Drupal\Core\StackMiddleware\NegotiationMiddleware->handle(Object, 1, 1) (Line: 23)
Stack\StackedHttpKernel->handle(Object, 1, 1) (Line: 694)
Drupal\Core\DrupalKernel->handle(Object) (Line: 19)
- Notice: Only variables should be passed by reference in Drupal\esante_lists\EsanteListsUtils::getArboImage() (line 41 of modules/custom/lists/src/EsanteListsUtils.php).
Drupal\esante_lists\EsanteListsUtils::getArboImage(Object, , 'image_490') (Line: 36)
Drupal\esante_lists\EsanteListsUtils::node_field_img_fallback(Object) (Line: 261)
esante_lists_node_view_alter(Array, Object, Object) (Line: 539)
Drupal\Core\Extension\ModuleHandler->alter('node_view', Array, Object, Object) (Line: 316)
Drupal\Core\Entity\EntityViewBuilder->buildMultiple(Array) (Line: 250)
Drupal\Core\Entity\EntityViewBuilder->build(Array)
call_user_func_array(Array, Array) (Line: 100)
Drupal\Core\Render\Renderer->doTrustedCallback(Array, Array, 'Render #pre_render callbacks must be methods of a class that implements \Drupal\Core\Security\TrustedCallbackInterface or be an anonymous function. The callback was %s. Support for this callback implementation is deprecated in 8.8.0 and will be removed in Drupal 9.0.0. See https://www.drupal.org/node/2966725', 'silenced_deprecation', 'Drupal\Core\Render\Element\RenderCallbackInterface') (Line: 781)
Drupal\Core\Render\Renderer->doCallback('#pre_render', Array, Array) (Line: 372)
Drupal\Core\Render\Renderer->doRender(Array, ) (Line: 200)
Drupal\Core\Render\Renderer->render(Array, ) (Line: 226)
Drupal\Core\Render\MainContent\HtmlRenderer->Drupal\Core\Render\MainContent\{closure}() (Line: 573)
Drupal\Core\Render\Renderer->executeInRenderContext(Object, Object) (Line: 227)
Drupal\Core\Render\MainContent\HtmlRenderer->prepare(Array, Object, Object) (Line: 117)
Drupal\Core\Render\MainContent\HtmlRenderer->renderResponse(Array, Object, Object) (Line: 90)
Drupal\Core\EventSubscriber\MainContentViewSubscriber->onViewRenderArray(Object, 'kernel.view', Object)
call_user_func(Array, Object, 'kernel.view', Object) (Line: 111)
Drupal\Component\EventDispatcher\ContainerAwareEventDispatcher->dispatch('kernel.view', Object) (Line: 156)
Symfony\Component\HttpKernel\HttpKernel->handleRaw(Object, 1) (Line: 68)
Symfony\Component\HttpKernel\HttpKernel->handle(Object, 1, 1) (Line: 57)
Drupal\Core\StackMiddleware\Session->handle(Object, 1, 1) (Line: 47)
Drupal\Core\StackMiddleware\KernelPreHandle->handle(Object, 1, 1) (Line: 47)
Drupal\Core\StackMiddleware\ReverseProxyMiddleware->handle(Object, 1, 1) (Line: 52)
Drupal\Core\StackMiddleware\NegotiationMiddleware->handle(Object, 1, 1) (Line: 23)
Stack\StackedHttpKernel->handle(Object, 1, 1) (Line: 694)
Drupal\Core\DrupalKernel->handle(Object) (Line: 19)
- Notice: Undefined offset: 0 in esante_theme_preprocess_node() (line 353 of themes/esante_theme/esante_theme.theme).
esante_theme_preprocess_node(Array, 'node', Array) (Line: 287)
Drupal\Core\Theme\ThemeManager->render('node', Array) (Line: 431)
Drupal\Core\Render\Renderer->doRender(Array, ) (Line: 200)
Drupal\Core\Render\Renderer->render(Array, ) (Line: 226)
Drupal\Core\Render\MainContent\HtmlRenderer->Drupal\Core\Render\MainContent\{closure}() (Line: 573)
Drupal\Core\Render\Renderer->executeInRenderContext(Object, Object) (Line: 227)
Drupal\Core\Render\MainContent\HtmlRenderer->prepare(Array, Object, Object) (Line: 117)
Drupal\Core\Render\MainContent\HtmlRenderer->renderResponse(Array, Object, Object) (Line: 90)
Drupal\Core\EventSubscriber\MainContentViewSubscriber->onViewRenderArray(Object, 'kernel.view', Object)
call_user_func(Array, Object, 'kernel.view', Object) (Line: 111)
Drupal\Component\EventDispatcher\ContainerAwareEventDispatcher->dispatch('kernel.view', Object) (Line: 156)
Symfony\Component\HttpKernel\HttpKernel->handleRaw(Object, 1) (Line: 68)
Symfony\Component\HttpKernel\HttpKernel->handle(Object, 1, 1) (Line: 57)
Drupal\Core\StackMiddleware\Session->handle(Object, 1, 1) (Line: 47)
Drupal\Core\StackMiddleware\KernelPreHandle->handle(Object, 1, 1) (Line: 47)
Drupal\Core\StackMiddleware\ReverseProxyMiddleware->handle(Object, 1, 1) (Line: 52)
Drupal\Core\StackMiddleware\NegotiationMiddleware->handle(Object, 1, 1) (Line: 23)
Stack\StackedHttpKernel->handle(Object, 1, 1) (Line: 694)
Drupal\Core\DrupalKernel->handle(Object) (Line: 19)
- Notice: Undefined variable: tid in esante_theme_preprocess_node() (line 376 of themes/esante_theme/esante_theme.theme).
esante_theme_preprocess_node(Array, 'node', Array) (Line: 287)
Drupal\Core\Theme\ThemeManager->render('node', Array) (Line: 431)
Drupal\Core\Render\Renderer->doRender(Array, ) (Line: 200)
Drupal\Core\Render\Renderer->render(Array, ) (Line: 226)
Drupal\Core\Render\MainContent\HtmlRenderer->Drupal\Core\Render\MainContent\{closure}() (Line: 573)
Drupal\Core\Render\Renderer->executeInRenderContext(Object, Object) (Line: 227)
Drupal\Core\Render\MainContent\HtmlRenderer->prepare(Array, Object, Object) (Line: 117)
Drupal\Core\Render\MainContent\HtmlRenderer->renderResponse(Array, Object, Object) (Line: 90)
Drupal\Core\EventSubscriber\MainContentViewSubscriber->onViewRenderArray(Object, 'kernel.view', Object)
call_user_func(Array, Object, 'kernel.view', Object) (Line: 111)
Drupal\Component\EventDispatcher\ContainerAwareEventDispatcher->dispatch('kernel.view', Object) (Line: 156)
Symfony\Component\HttpKernel\HttpKernel->handleRaw(Object, 1) (Line: 68)
Symfony\Component\HttpKernel\HttpKernel->handle(Object, 1, 1) (Line: 57)
Drupal\Core\StackMiddleware\Session->handle(Object, 1, 1) (Line: 47)
Drupal\Core\StackMiddleware\KernelPreHandle->handle(Object, 1, 1) (Line: 47)
Drupal\Core\StackMiddleware\ReverseProxyMiddleware->handle(Object, 1, 1) (Line: 52)
Drupal\Core\StackMiddleware\NegotiationMiddleware->handle(Object, 1, 1) (Line: 23)
Stack\StackedHttpKernel->handle(Object, 1, 1) (Line: 694)
Drupal\Core\DrupalKernel->handle(Object) (Line: 19)
- Warning: array_flip(): Can only flip STRING and INTEGER values! in Drupal\Core\Entity\EntityStorageBase->loadMultiple() (line 266 of core/lib/Drupal/Core/Entity/EntityStorageBase.php).
Drupal\Core\Entity\EntityStorageBase->loadMultiple(Array) (Line: 250)
Drupal\Core\Entity\EntityStorageBase->load() (Line: 532)
Drupal\Core\Entity\EntityBase::load() (Line: 67)
Drupal\esante_guides\Plugin\Block\EsanteGuidesBlockRubrique->build() (Line: 171)
Drupal\block\BlockViewBuilder::preRender(Array)
call_user_func_array(Array, Array) (Line: 100)
Drupal\Core\Render\Renderer->doTrustedCallback(Array, Array, 'Render #pre_render callbacks must be methods of a class that implements \Drupal\Core\Security\TrustedCallbackInterface or be an anonymous function. The callback was %s. Support for this callback implementation is deprecated in 8.8.0 and will be removed in Drupal 9.0.0. See https://www.drupal.org/node/2966725', 'silenced_deprecation', 'Drupal\Core\Render\Element\RenderCallbackInterface') (Line: 781)
Drupal\Core\Render\Renderer->doCallback('#pre_render', Array, Array) (Line: 372)
Drupal\Core\Render\Renderer->doRender(Array, 1) (Line: 200)
Drupal\Core\Render\Renderer->render(Array, 1) (Line: 156)
Drupal\Core\Render\Renderer->Drupal\Core\Render\{closure}() (Line: 573)
Drupal\Core\Render\Renderer->executeInRenderContext(Object, Object) (Line: 157)
Drupal\Core\Render\Renderer->renderPlain(Array) (Line: 171)
Drupal\Core\Render\Renderer->renderPlaceholder('', Array) (Line: 658)
Drupal\Core\Render\Renderer->replacePlaceholders(Array) (Line: 543)
Drupal\Core\Render\Renderer->doRender(Array, 1) (Line: 200)
Drupal\Core\Render\Renderer->render(Array, 1) (Line: 144)
Drupal\Core\Render\Renderer->Drupal\Core\Render\{closure}() (Line: 573)
Drupal\Core\Render\Renderer->executeInRenderContext(Object, Object) (Line: 145)
Drupal\Core\Render\Renderer->renderRoot(Array) (Line: 282)
Drupal\Core\Render\HtmlResponseAttachmentsProcessor->renderPlaceholders(Object) (Line: 131)
Drupal\Core\Render\HtmlResponseAttachmentsProcessor->processAttachments(Object) (Line: 45)
Drupal\Core\EventSubscriber\HtmlResponseSubscriber->onRespond(Object, 'kernel.response', Object)
call_user_func(Array, Object, 'kernel.response', Object) (Line: 111)
Drupal\Component\EventDispatcher\ContainerAwareEventDispatcher->dispatch('kernel.response', Object) (Line: 191)
Symfony\Component\HttpKernel\HttpKernel->filterResponse(Object, Object, 1) (Line: 173)
Symfony\Component\HttpKernel\HttpKernel->handleRaw(Object, 1) (Line: 68)
Symfony\Component\HttpKernel\HttpKernel->handle(Object, 1, 1) (Line: 57)
Drupal\Core\StackMiddleware\Session->handle(Object, 1, 1) (Line: 47)
Drupal\Core\StackMiddleware\KernelPreHandle->handle(Object, 1, 1) (Line: 47)
Drupal\Core\StackMiddleware\ReverseProxyMiddleware->handle(Object, 1, 1) (Line: 52)
Drupal\Core\StackMiddleware\NegotiationMiddleware->handle(Object, 1, 1) (Line: 23)
Stack\StackedHttpKernel->handle(Object, 1, 1) (Line: 694)
Drupal\Core\DrupalKernel->handle(Object) (Line: 19)
